Leila Shirazi: Assistant Clinical Professor and Associate Chief of Pediatric Optometry
We are pleased to announce Dr. Shirazi is featured on the Women of UCSF website.
Read her inspiring story here:
https://womenofucsfhealth.ucsf.edu/blog/leila-h-shirazi-od-faao
Project Title: Elucidating Mechanisms of Visual Pathway Damage in Alzheimer’s Disease
Project Title: Mechanisms of Retinal Degeneration in Alzheimer’s Disease-Related Dementias
Project Title: Enabling Direct Correlation of Choroidal Blood Flow and Retinal Degeneration at the Single Vessel Level and Over Time Using Transscleral Multiphoton Microscopy
Project Title: Transcutaneous Orbicularis Oculi Stimulation for Temporary Eyelid Closure
Juvenile X-linked retinoschisis (XLRS) is an inherited retinal disorder (IRD) that predominantly affects boys and men, arising in early childhood with potential blindness by their teens or adulthood. While there are few medication options for IRDs, XLRS responds well to carbonic anhydrase inhibitor (CAI) treatment. Treatment with eye drops has been effective but is unable to fully penetrate the eye and dependent on patient application. This project aims to develop a minimally invasive injectable device to provide CAI therapy for 6–12 months, offering a better treatment approach.

Multiphoton Aqueous Flowmetry and Image-Guided Laser Therapy: Novel Approaches for Glaucoma Precision Medicine. 
Diabetic retinopathy is a critical eye disease that poses a significant threat to vision if left untreated. To address the issue of inadequate preventive care and the absence of a reliable method to predict high-risk patients, ophthalmologist Cathy Sun, MD, and her team at UCSF embarked on a groundbreaking study. Their aim was to develop predictive models for the progression of diabetic retinopathy, enabling healthcare providers to implement timely interventions and prevent vision loss in affected individuals.


How did Hodgkin’s disease shape your career? I was a classic “Caltech nerd,” pursuing math and physics, when I was diagnosed with cancer. Fortunately, my treatment was effective, and I got a second chance at life. Becoming a clinician and medical researcher became my way of giving back.