The Lamba Lab
Focusing on retinal repair and modeling disease with stem cells technologies
Selected Publications
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Generation of Transplantable Retinal Photoreceptors from a Current Good Manufacturing Practice-Manufactured Human Induced Pluripotent Stem Cell Line. Zhu J, Reynolds J, Garcia T, Cifuentes H, Chew S, Zeng X, Lamba DA. Stem cells translational medicine. 2018; 7(2):210-219.
Immunosuppression via loss of IL2rg enhances long-term functional integration of hESC-derived photoreceptors in mouse retina. Zhu J, Cifuentes H, Reynolds J, Lamba DA. Cell Stem Cell 2017 20 1-11.
Immune modulation by MANF promotes tissue repair and regenerative success in the retina. Neves J, Zhu J, Sousa-Victor P, Konjikusic M, Riley R, Chew S, Qi Y, Jasper H, Lamba DA. Science. 2016 Jul 1;353(6294):aaf3646
Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice. Lamba DA, Reh TA, Gust J.(2009). Cell Stem Cell. 4(1):73-9.
Efficient generation of retinal progenitor cells from human embryonic stem cells. Lamba DA, Karl MO, Ware CB, Reh TA. (2006). Proc Natl Acad Sci USA;103:12769-12774.