8:30-9:15am–Case Presentations: Comprehensive (Saras Ramanathan, MD)

9:15-10:00am–Grand Rounds Lecture: “Elucidating Disease Mechanisms and Therapeutic Targets by CRISPR-Based Functional Genomics”, Martin Kampmann, PhD

Host: Aparna Lakkaraju, PhD

• Introduction to CRISPR-Based Functional Genomics
• Application of CRISPR-Based Functional Genomics to iPSC-Based Models of Disease
• Links Between Lipofuscin and Ferroptosis in Human Neurons

Accreditation: The University of California, San Francisco School of Medicine (UCSF) is accredited by the Accreditation Council for ContinuingMedical Education to provide continuing medical education for physicians.  UCSF designates this live activity for a maximum of 1.5AMA PRA Category 1 Credits.™ Physicians should only claim credit commensurate with the extent of their participation in the activity. You must complete an evaluation to qualify for CME credit.

Faculty Relationship Disclosure: Planners Stephen McLeod, MD and Yvonne Ou, MD have stated they have no financial relationships to disclose. Speaker Martin Kampmann, PhD has stated they have no relationships to disclose.

Commercial Support Disclosure: No commercial support was received for this Grand Rounds presentation.  This CME activity complies with AM1195.

This presentation is supported by the Samuel J. Kimura fund.